Uses of Pari 25mg Tablet CR

Pari 25mg Tablet CR is used for the treatment or prevention of the following disease(s):

Depression, Obsessive Compulsive Disorder, Anxiety Disorder, Premenstrual Dysphoric Disorder

Side effects of Pari 25mg Tablet CR

Precautions while taking Pari 25mg Tablet CR

Dosage of Pari 25mg Tablet CR

Overdose of Pari 25mg Tablet CR

Onset of Action of Pari 25mg Tablet CR

Duration of Action of Pari 25mg Tablet CR

Precautions & Warnings


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All substitutes for Pari 25mg Tablet CR

For information purpose only. Refer to a healthcare professionals before consuming any medicines and/or drugs.


Drug :- antacids: Hastened release of C.R. paroxetine aspirin, NSAIDs, warfarin: Increased anticoagulant activity and risk of bleeding.

astemizole: Increased risk of arrhythmias.

atomoxetine, risperidone, other drugs metabolized by CYP2D6, such as amitriptyline, desipramine, fluoxetine, imipramine, phenothiazines, tamoxifen, type IC antiarrhythmics: Increased plasma levels of these drugs.

barbiturates, primidone: Decreased blood paroxetine level.

cimetidine: Possibly increased blood paroxetine level.

cisapride, isoniazid, MAO inhibitors, procarbazine: Possibly serotonin syndrome.

codeine, haloperidol, metoprolol, perphenazine, propranolol, risperidone, thioridazine: Decreased metabolism and increased effects of these drugs.

cyproheptadine: Decreased paroxetine effects.

dextromethorphan: Decreased dextromethorphan metabolism and increased risk of toxicity.

digoxin: Possibly decreased digoxin effects.

encainide, flecainide, propafenone, quinidine: Potentiated toxicity of these drugs.

fosamprenavir, ritonavir: Decreased plasma paroxetine level.

lithium: Possibly increased blood paroxetine level, increased risk of serotonin syndrome.

methadone: Decreased methadone metabolism, increased risk of adverse effects.

phenytoin: Possibly phenytoin toxicity.

pimozide: Increased risk of prolonged QT interval.

procyclidine: Increased blood procyclidine level and anticholinergic effects.

serotonergic drugs such as linezolid, St. John's wort, tramadol, triptans, and tryptophan: Increased risk of serotonin syndrome.

tamoxifen: Decreased tamoxifen effectiveness.

theophylline: Possibly increased blood theophylline level and risk of toxicity.

thioridazine: Increased thioridazine level, possibly leading to prolonged QT interval and life-threatening ventricular arrhythmias.

tramadol: Increased risk of serotonin syndrome and seizures.

tricyclic antidepressants: Increased metabolism and blood antidepressant levels, increased risk of toxicity, including seizures.

Sonu Kumar is a registered pharmacist with Bihar State Pharmacy Council with over 6 months experience. He is a medicine content contributor at

Dr. Nilanjan Chandra is a talented Psychiatrist, Psychotherapist, De-addiction specialist, and Sex Therapist with 10 years of experience. He's currently practicing as a Consultant Neuro-psychiatrist at Institute of Neurosciences, Kolkata. He completed his MBBS from Calcutta National Medical College in 2011 and MD from Government Medical College and New Civil Hospital, Surat in 2016.