Uses of Stemetil 12.5mg Injection

Stemetil 12.5mg Injection is used for the treatment or prevention of the following disease(s):

Nausea, Vomiting , Schizophrenia, Anxiety

Side effects of Stemetil 12.5mg Injection

Precautions while taking Stemetil 12.5mg Injection

Dosage of Stemetil 12.5mg Injection

Overdose of Stemetil 12.5mg Injection

Onset of Action of Stemetil 12.5mg Injection

Duration of Action of Stemetil 12.5mg Injection

Precautions & Warnings


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Drug :- aluminum- or magnesium-containing antacids, antidiarrheals adsorbent: Possibly inhibited absorption of oral prochlorperazine amantadine, anticholinergics, antidyskinetics, antihistamines: Possibly intensified anticholinergic adverse effects, increased risk of prochlorperazine-induced hyperpyretic effect.

amphetamines: Decreased stimulant effect of amphetamines, decreased antipsychotic effect of prochlorperazine.

anticonvulsants: Lowered seizure threshold.

antithyroid drugs: Increased risk of agranulocytosis.

apomorphine: Possibly decreased emetic response to apomorphine, additive CNS depression.

appetite suppressants: Possibly antagonized anorectic effect of appetite suppressants.except for phenmetrazine.

astemizole, cisapride, disopyramide, erythromycin, pimozide, probucol, procainamide: Additive QT interval prolongation, increased risk of ventricular tachycardia.

beta blockers: Increased risk of additive hypotensive effects, irreversible retinopathy, arrhythmias, and tardive dyskinesia.

bromocriptine: Decreased effectiveness of bromocriptine.

CNS depressants: Additive CNS depression.

dopamine: Possibly antagonized peripheral vasoconstriction high doses of dopamine.

ephedrine, epinephrine: Decreased vasopressor effects of these drugs.

hepatotoxic drugs: Increased risk of hepatotoxicity.

hypotension-producing drugs: Possibly severe hypotension with syncope.

levodopa: Inhibited antidyskinetic effect of levodopa.

lithium: Reduced absorption of oral prochlorperazine, increased lithium excretion, increased extrapyramidal effects, possibly masking of early symptoms of lithium toxicity. MAO inhibitors, maprotiline, tricyclic antidepressants: Possibly prolonged and intensified anticholinergic and sedative effects, increased antidepressant level, inhibited prochlorperazine metabolism, increased risk of neuroleptic malignant syndrome.

mephentermine: Possibly antagonized antipsychotic effect of prochlorperazine and vasopressor effect of mephentermine.

metrizamide: Increased risk of seizures.

opioid analgesics: Increased risk of CNS and respiratory depression, orthostatic hypotension, severe constipation, urine retention.

ototoxic drugs: Possibly masking of some symptoms of ototoxicity, such as dizziness, tinnitus, and vertigo.

phenytoin: Possibly inhibited phenytoin.

metabolism, increased risk of phenytoin toxicity.

thiazide diuretics: Possibly potentiated hyponatremia and water intoxication.

Activity :- alcohol use: Additive CNS depression.

Kunal is a registered pharmacist with RGUHS with over 4 years experience. He is a medicine content contributor at

Dr. Nilanjan Chandra is a talented Psychiatrist, Psychotherapist, De-addiction specialist, and Sex Therapist with 10 years of experience. He's currently practicing as a Consultant Neuro-psychiatrist at Institute of Neurosciences, Kolkata. He completed his MBBS from Calcutta National Medical College in 2011 and MD from Government Medical College and New Civil Hospital, Surat in 2016.